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THOP1 Antibody

Catalog Number:

47258
other_names: TOP; MP78; EP24.15; MEPD_HUMAN

Amount:

100μg
calculated_mw: 79 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P52888
NCBI Gene ID:7064
Gene Accssion:BC013878

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human THOP1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total THOP1 protein.

Applications:

WB, IHC

Background:

The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides.

References:

appl_detail:

WB dilution:1:200-1000
IHC dilution:1: 30-150

Datasheet PDF

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