Product Datasheet
THOP1 Antibody
Catalog Number: 47258
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P52888
NCBI Gene ID:7064
Gene Accssion:BC013878
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human THOP1
- appl_detail:
- WB dilution:1:200-1000
IHC dilution:1: 30-150
- other_names:
- TOP; MP78; EP24.15; MEPD_HUMAN
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total THOP1 protein.
- Background:
- The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides.
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