RIOX2 Antibody

Catalog Number:

47191

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q8IUF8
NCBI Gene ID:84864
Gene Accssion:BC014928

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human RIOX2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total RIOX2 protein.

Applications:

WB, IHC

Background:

Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.

References:

appl_detail:

Western blotting:1:200-1000
Immunofluorescence:1: 25-100

Datasheet PDF