Product Datasheet
RIOX2 Antibody
Catalog Number: 47191
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8IUF8
NCBI Gene ID:84864
Gene Accssion:BC014928
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human RIOX2
- appl_detail:
- Western blotting:1:200-1000
Immunofluorescence:1: 25-100
- other_names:
- ROX; MDIG; MINA; NO52; JMJD10; MINA53
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total RIOX2 protein.
- Background:
- Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
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