DUSP27 Antibody

Catalog Number:

47083

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q5VZP5
NCBI Gene ID:92235
Gene Accssion:NP_001073895

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DUSP27

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DUSP27 protein.

Applications:

IHC

Background:

Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.

References:

appl_detail:

Immunofluorescence:1: 40-200

Datasheet PDF