Product Datasheet  
DUSP27 Antibody  
Catalog Number: 47083  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q5VZP5
    NCBI Gene ID:92235
    Gene Accssion:NP_001073895
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20C
  • Immunogen:  
  • Synthetic peptide of human DUSP27
  • reactivity:  
  • Hu
  • appl_detail:  

  • Immunofluorescence:1: 40-200
  • other_names:  
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total DUSP27 protein.
  • Applications:  
  • IHC
  • Background:  
  • Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.



 
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