DNAJB4 Antibody

Catalog Number:

47067

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UDY4
NCBI Gene ID:11080
Gene Accssion:NP_008965

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DNAJB4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DNAJB4 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Immunofluorescence:1: 20-100

Datasheet PDF