Product Datasheet  
DNAJB4 Antibody  
Catalog Number: 47067  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9UDY4
    NCBI Gene ID:11080
    Gene Accssion:NP_008965
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20C
  • Immunogen：  
  • Synthetic peptide of human DNAJB4
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunofluorescence:1: 20-100
  • other_names：  
  • DjB4; HLJ1; DNAJW
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total DNAJB4 protein.
  • Applications：  
  • IHC
  • Background：  
  • The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.



 
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