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DACT1 Antibody

Catalog Number:

47013
other_names: DPR1; FRODO; HDPR1; DAPPER; THYEX3; DAPPER1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9NYF0
NCBI Gene ID:51339
Gene Accssion:NP_057735

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DACT1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DACT1 protein.

Applications:

IHC

Background:

The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene.

References:

appl_detail:


Immunofluorescence:1: 20-100

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