Product Datasheet
DACT1 Antibody
Catalog Number: 47013
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9NYF0
NCBI Gene ID:51339
Gene Accssion:NP_057735
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human DACT1
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- DPR1; FRODO; HDPR1; DAPPER; THYEX3; DAPPER1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total DACT1 protein.
- Background:
- The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene.
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