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VTI1A Antibody

Catalog Number:

46706
other_names: MMDS3; MVti1; VTI1RP2; Vti1-rp2

Amount:

100μg
calculated_mw: 25 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q96AJ9
NCBI Gene ID:143187
NCBI Protein:BC017052

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human VTI1A

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total VTI1A protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 25-100

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