Product Datasheet
VTI1A Antibody
Catalog Number: 46706
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q96AJ9
NCBI Gene ID:143187
NCBI Protein:BC017052
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human VTI1A
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 25-100
- other_names:
- MMDS3; MVti1; VTI1RP2; Vti1-rp2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total VTI1A protein.
- Background:
- The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.
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