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UBE2M Antibody

Catalog Number:

46690
other_names: UBC12; hUbc12; UBC-RS2

Amount:

100μg
calculated_mw: 21 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:P61081
NCBI Gene ID:9040
NCBI Protein:BC058924

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human UBE2M

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total UBE2M protein.

Applications:

WB IHC

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.?

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 25-100

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