Product Datasheet
UBE2M Antibody
Catalog Number: 46690
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P61081
NCBI Gene ID:9040
NCBI Protein:BC058924
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to residues near the C terminal of human UBE2M
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 25-100
- other_names:
- UBC12; hUbc12; UBC-RS2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total UBE2M protein.
- Background:
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.?
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