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STS Antibody

Catalog Number:

46679
other_names: ES; ASC; XLI; ARSC; SSDD; ARSC1

Amount:

100μg
calculated_mw: 65 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:P08842
NCBI Gene ID:412
NCBI Protein:NP_000342

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human STS

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total STS protein.

Applications:

WB IHC

Background:

This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 10-50

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