Product Datasheet
STS Antibody
Catalog Number: 46679
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P08842
NCBI Gene ID:412
NCBI Protein:NP_000342
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to internal residues of human STS
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 10-50
- other_names:
- ES; ASC; XLI; ARSC; SSDD; ARSC1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total STS protein.
- Background:
- This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene.
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