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SLC5A8 Antibody

Catalog Number:

46671
other_names: AIT; SMCT; SMCT1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8N695
NCBI Gene ID:160728
NCBI Protein:NP_666018

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human SLC5A8

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLC5A8 protein.

Applications:

IHC

Background:

SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions as a high-affinity sodium-coupled lactate transporter involved in reabsorption of lactate and maintenance of blood lactate levels (Thangaraju et al., 2006 [PubMed 16873376]).

References:

appl_detail:


Immunohistochemistry: 1: 25-100

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