Product Datasheet
SLC5A8 Antibody
Catalog Number: 46671
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8N695
NCBI Gene ID:160728
NCBI Protein:NP_666018
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human SLC5A8
- appl_detail:
Immunohistochemistry: 1: 25-100
- other_names:
- AIT; SMCT; SMCT1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total SLC5A8 protein.
- Background:
- SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions as a high-affinity sodium-coupled lactate transporter involved in reabsorption of lactate and maintenance of blood lactate levels (Thangaraju et al., 2006 [PubMed 16873376]).
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