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RTN4IP1 Antibody

Catalog Number:

46663
other_names: NIMP; OPA10

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8WWV3
NCBI Gene ID:84816
NCBI Protein:NP_116119

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human RTN4IP1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total RTN4IP1 protein.

Applications:

IHC

Background:

This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, mental retardation, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants.

References:

appl_detail:


Immunohistochemistry: 1: 40-200

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