Product Datasheet
RTN4IP1 Antibody
Catalog Number: 46663
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8WWV3
NCBI Gene ID:84816
NCBI Protein:NP_116119
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to internal residues of human RTN4IP1
- appl_detail:
Immunohistochemistry: 1: 40-200
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total RTN4IP1 protein.
- Background:
- This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, mental retardation, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants.
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