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NELFB Antibody

Catalog Number:

46625
other_names: COBRA1; NELF-B

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8WX92
NCBI Gene ID:25920
NCBI Protein:NP_056271

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human NELFB

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total NELFB protein.

Applications:

IHC

Background:

NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]

References:

appl_detail:


Immunohistochemistry: 1: 25-100

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