Product Datasheet
NELFB Antibody
Catalog Number: 46625
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8WX92
NCBI Gene ID:25920
NCBI Protein:NP_056271
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to internal residues of human NELFB
- appl_detail:
Immunohistochemistry: 1: 25-100
- other_names:
- COBRA1; NELF-B
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total NELFB protein.
- Background:
- NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]
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