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NCBP1 Antibody

Catalog Number:

46622
other_names: NCBP; Sto1; CBP80

Amount:

100μg
calculated_mw: 92 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q09161
NCBI Gene ID:4686
NCBI Protein:NP_002477

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human NCBP1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total NCBP1 protein.

Applications:

WB IHC

Background:

The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 25-100

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