Product Datasheet
NCBP1 Antibody
Catalog Number: 46622
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q09161
NCBI Gene ID:4686
NCBI Protein:NP_002477
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human NCBP1
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 25-100
- other_names:
- NCBP; Sto1; CBP80
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total NCBP1 protein.
- Background:
- The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.
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