MYCN Antibody

Catalog Number:

46618

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P04198
NCBI Gene ID:4613
NCBI Protein:NP_005369

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human MYCN

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MYCN protein.

Applications:

WB

Background:

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF