IBA57 Antibody

Catalog Number:

46583

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q5T440
NCBI Gene ID:200205
NCBI Protein:NP_001010867

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human IBA57

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total IBA57 protein.

Applications:

IHC

Background:

The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.?

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF