Product Datasheet
IBA57 Antibody
Catalog Number: 46583
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q5T440
NCBI Gene ID:200205
NCBI Protein:NP_001010867
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to internal residues of human IBA57
- appl_detail:
Immunohistochemistry: 1: 30-150
- other_names:
- MMDS3; SPG74; C1orf69
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total IBA57 protein.
- Background:
- The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.?
© Signalway Biotechnology All Rights Reserved.