DNAJC2 Antibody

Catalog Number:

46553

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q99543
NCBI Gene ID:27000
NCBI Protein:NP_055192

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human DNAJC2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DNAJC2 protein.

Applications:

IHC

Background:

This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.?

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF