CNGA4 Antibody

Catalog Number:

46522

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8IV77
NCBI Gene ID:1262
NCBI Protein:NP_001032406

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CNGA4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CNGA4 protein.

Applications:

WB

Background:

Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF