Product Datasheet  
CNGA4 Antibody  
Catalog Number: 46522  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q8IV77
    NCBI Gene ID:1262
    NCBI Protein:NP_001032406
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human CNGA4
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:200-1:1000
  • other_names：  
  • CNG4; CNG5; CNCA2; CNG-4; CNGB2; OCNC2; OCNCb; OCNCBETA
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total CNGA4 protein.
  • Applications：  
  • WB
  • Background：  
  • Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.



 
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