CHURC1 Antibody

Catalog Number:

46499

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8WUH1
NCBI Gene ID:91612
NCBI Protein:NP_001190992

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human CHURC1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CHURC1 protein.

Applications:

IHC

Background:

CHURC1, also known as protein Churchill, is a 112 amino acid protein that plays a critical role in neural induction during embryogenesis. The fibroblast growth family of proteins (FGFs) has been identified as necessary factors in mesoderm formation and neural induction. CHURC1, a putative zinc finger protein, is a transcriptional activator that mediates FGF signaling. Furthermore, CHURC1 is thought to play a role in the regulation of cell movement. Although CHURC1 does not bind to DNA, it functions as a transcriptional regulator and a protein-interaction factor. Two isoforms of CHURC1 exist as a result of alternative splicing events.

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF