Product Datasheet
CHURC1 Antibody
Catalog Number: 46499
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8WUH1
NCBI Gene ID:91612
NCBI Protein:NP_001190992
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to internal residues of human CHURC1
- appl_detail:
Immunohistochemistry: 1: 25-100
- other_names:
- chch; My015; C14orf52
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CHURC1 protein.
- Background:
- CHURC1, also known as protein Churchill, is a 112 amino acid protein that plays a critical role in neural induction during embryogenesis. The fibroblast growth family of proteins (FGFs) has been identified as necessary factors in mesoderm formation and neural induction. CHURC1, a putative zinc finger protein, is a transcriptional activator that mediates FGF signaling. Furthermore, CHURC1 is thought to play a role in the regulation of cell movement. Although CHURC1 does not bind to DNA, it functions as a transcriptional regulator and a protein-interaction factor. Two isoforms of CHURC1 exist as a result of alternative splicing events.
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