Product Datasheet  
CHURC1 Antibody  
Catalog Number: 46499  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q8WUH1
    NCBI Gene ID:91612
    NCBI Protein:NP_001190992
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to internal residues of human CHURC1
  • reactivity:  
  • Hu
  • appl_detail:  

  • Immunohistochemistry: 1: 25-100
  • other_names:  
  • chch; My015; C14orf52
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total CHURC1 protein.
  • Applications:  
  • IHC
  • Background:  
  • CHURC1, also known as protein Churchill, is a 112 amino acid protein that plays a critical role in neural induction during embryogenesis. The fibroblast growth family of proteins (FGFs) has been identified as necessary factors in mesoderm formation and neural induction. CHURC1, a putative zinc finger protein, is a transcriptional activator that mediates FGF signaling. Furthermore, CHURC1 is thought to play a role in the regulation of cell movement. Although CHURC1 does not bind to DNA, it functions as a transcriptional regulator and a protein-interaction factor. Two isoforms of CHURC1 exist as a result of alternative splicing events.



 
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