CHMP5 Antibody

Catalog Number:

46492

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NZZ3
NCBI Gene ID:51510
NCBI Protein:BC007457

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human CHMP5

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CHMP5 protein.

Applications:

IHC

Background:

CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).

References:

appl_detail:

Immunohistochemistry: 1: 25-100

Datasheet PDF