Product Datasheet
CHMP5 Antibody
Catalog Number: 46492
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9NZZ3
NCBI Gene ID:51510
NCBI Protein:BC007457
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human CHMP5
- appl_detail:
Immunohistochemistry: 1: 25-100
- other_names:
- Vps60; CGI-34; PNAS-2; C9orf83; HSPC177; SNF7DC2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CHMP5 protein.
- Background:
- CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
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