Product Datasheet  
CHMP5 Antibody  
Catalog Number: 46492  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q9NZZ3
    NCBI Gene ID:51510
    NCBI Protein:BC007457
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Full length fusion protein of human CHMP5
  • reactivity:  
  • Hu
  • appl_detail:  

  • Immunohistochemistry: 1: 25-100
  • other_names:  
  • Vps60; CGI-34; PNAS-2; C9orf83; HSPC177; SNF7DC2
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total CHMP5 protein.
  • Applications:  
  • IHC
  • Background:  
  • CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).



 
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