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CDT1 Antibody

Catalog Number:

46460
other_names: DUP; RIS2

Amount:

100μg
calculated_mw: 60 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9H211
NCBI Gene ID:81620
NCBI Protein:NP_112190

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CDT1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CDT1 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 30-150

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