Product Datasheet
CDT1 Antibody
Catalog Number: 46460
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9H211
NCBI Gene ID:81620
NCBI Protein:NP_112190
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human CDT1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 30-150
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CDT1 protein.
- Background:
- The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.
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