1-832-868-1888
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Catalog Number: |
46457 |
| other_names: | |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:Q96HQ2 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
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Immunogen: |
Synthetic protein corresponding to residues near the N terminal of human CDKN2AIPNL |
Purification: |
Antigen affinity purification |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total CDKN2AIPNL protein. |
Applications: |
IHC |
Background: |
CDKN2AIPNL (CDKN2A interacting protein N-terminal like) is a 116 amino acid protein that belongs to the CARF family. Existing as two alternatively spliced isoforms, CDKN2AIPNL is encoded by a gene that maps to human chromosome 5q31.1. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
References: |
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appl_detail: |
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