Product Datasheet
CDKN2AIPNL Antibody
Catalog Number: 46457
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q96HQ2
NCBI Gene ID:91368
NCBI Protein:BC018086
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to residues near the N terminal of human CDKN2AIPNL
- appl_detail:
Immunohistochemistry: 1: 25-100
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CDKN2AIPNL protein.
- Background:
- CDKN2AIPNL (CDKN2A interacting protein N-terminal like) is a 116 amino acid protein that belongs to the CARF family. Existing as two alternatively spliced isoforms, CDKN2AIPNL is encoded by a gene that maps to human chromosome 5q31.1. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
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