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XPO1 Antibody

Catalog Number:

46711
other_names: emb; CRM1; exp1

Amount:

100μg
calculated_mw: 123 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:O14980
NCBI Gene ID:7514
NCBI Protein:NP_003391

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human XPO1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total XPO1 protein.

Applications:

WB IHC

Background:

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 30-150

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