Product Datasheet
XPO1 Antibody
Catalog Number: 46711
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O14980
NCBI Gene ID:7514
NCBI Protein:NP_003391
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human XPO1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 30-150
- other_names:
- emb; CRM1; exp1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total XPO1 protein.
- Background:
- This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
© Signalway Biotechnology All Rights Reserved.