Product Datasheet  
XPO1 Antibody  
Catalog Number: 46711  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:O14980
    NCBI Gene ID:7514
    NCBI Protein:NP_003391
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to residues near the C terminal of human XPO1
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1: 30-150
  • other_names:  
  • emb; CRM1; exp1
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total XPO1 protein.
  • Applications:  
  • WB IHC
  • Background:  
  • This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.



 
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