1-832-868-1888
order@swbio.com

Catalog Number: |
46709 |
| other_names: | ALFY; ZFYVE25 |
Amount: |
100μg |
| calculated_mw: | 395 kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:Q8IZQ1 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Synthetic protein corresponding to residues near the C terminal of human WDFY3 |
Purification: |
Antigen affinity purification |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total WDFY3 protein. |
Applications: |
WB IHC |
Background: |
This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. |
References: |
|
appl_detail: |
Western blotting: 1:200-1:1000 |
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