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WDFY3 Antibody

Catalog Number:

46709
other_names: ALFY; ZFYVE25

Amount:

100μg
calculated_mw: 395 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8IZQ1
NCBI Gene ID:23001
NCBI Protein:BC015214

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human WDFY3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total WDFY3 protein.

Applications:

WB IHC

Background:

This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 50-300

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