Product Datasheet
WDFY3 Antibody
Catalog Number: 46709
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8IZQ1
NCBI Gene ID:23001
NCBI Protein:BC015214
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to residues near the C terminal of human WDFY3
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 50-300
- other_names:
- ALFY; ZFYVE25
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total WDFY3 protein.
- Background:
- This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.
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