Product Datasheet  
WDFY3 Antibody  
Catalog Number: 46709  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q8IZQ1
    NCBI Gene ID:23001
    NCBI Protein:BC015214
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic protein corresponding to residues near the C terminal of human WDFY3
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1: 50-300
  • other_names:  
  • ALFY; ZFYVE25
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total WDFY3 protein.
  • Applications:  
  • WB IHC
  • Background:  
  • This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.



 
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