CBFA2T3 Antibody

Catalog Number:

46410

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O75081
NCBI Gene ID:863
NCBI Protein:NP_005178

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CBFA2T3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CBFA2T3 protein.

Applications:

IHC

Background:

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

References:

appl_detail:

Immunohistochemistry: 1: 30-150

Datasheet PDF