Product Datasheet  
CBFA2T3 Antibody  
Catalog Number: 46410  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:O75081
    NCBI Gene ID:863
    NCBI Protein:NP_005178
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human CBFA2T3
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1: 30-150
  • other_names：  
  • ETO2; MTG16; MTGR2; ZMYND4; RUNX1T3
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total CBFA2T3 protein.
  • Applications：  
  • IHC
  • Background：  
  • This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.



 
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