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CARS Antibody

Catalog Number:

46404
other_names: CARS1; CYSRS; MGC:11246

Amount:

100μg
calculated_mw: 85 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:P49589
NCBI Gene ID:833
NCBI Protein:BC002880

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the N terminal of human CARS

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CARS protein.

Applications:

WB

Background:

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.

References:

appl_detail:

Western blotting: 1:200-1:1000

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