Product Datasheet
CARS Antibody
Catalog Number: 46404
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P49589
NCBI Gene ID:833
NCBI Protein:BC002880
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to residues near the N terminal of human CARS
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- CARS1; CYSRS; MGC:11246
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CARS protein.
- Background:
- This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.
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