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CACNA1B Antibody

Catalog Number:

46382
other_names: BIII; CACNN; DYT23; Cav2.2; CACNL1A5

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q00975
NCBI Gene ID:774
NCBI Protein:NP_000709

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CACNA1B

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CACNA1B protein.

Applications:

IHC

Background:

The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene.?

References:

appl_detail:


Immunohistochemistry: 1: 25-100

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