Product Datasheet  
CACNA1B Antibody  
Catalog Number: 46382  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q00975
    NCBI Gene ID:774
    NCBI Protein:NP_000709
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to residues near the C terminal of human CACNA1B
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  

  • Immunohistochemistry: 1: 25-100
  • other_names:  
  • BIII; CACNN; DYT23; Cav2.2; CACNL1A5
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total CACNA1B protein.
  • Applications:  
  • IHC
  • Background:  
  • The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene.?



 
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