Product Datasheet
CACNA1B Antibody
Catalog Number: 46382
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q00975
NCBI Gene ID:774
NCBI Protein:NP_000709
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human CACNA1B
- appl_detail:
Immunohistochemistry: 1: 25-100
- other_names:
- BIII; CACNN; DYT23; Cav2.2; CACNL1A5
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CACNA1B protein.
- Background:
- The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene.?
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