CABIN1 Antibody

Catalog Number:

46380

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9Y6J0
NCBI Gene ID:23523
NCBI Protein:NP_036427

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to internal residues of human CABIN1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CABIN1 protein.

Applications:

IHC

Background:

Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.

References:

appl_detail:

Immunohistochemistry: 1: 40-200

Datasheet PDF