Product Datasheet  
CABIN1 Antibody  
Catalog Number: 46380  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q9Y6J0
    NCBI Gene ID:23523
    NCBI Protein:NP_036427
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to internal residues of human CABIN1
  • reactivity:  
  • Hu
  • appl_detail:  

  • Immunohistochemistry: 1: 40-200
  • other_names:  
  • CAIN; PPP3IN; KB-318B8.7
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total CABIN1 protein.
  • Applications:  
  • IHC
  • Background:  
  • Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.



 
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