Product Datasheet
CABIN1 Antibody
Catalog Number: 46380
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9Y6J0
NCBI Gene ID:23523
NCBI Protein:NP_036427
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to internal residues of human CABIN1
- appl_detail:
Immunohistochemistry: 1: 40-200
- other_names:
- CAIN; PPP3IN; KB-318B8.7
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CABIN1 protein.
- Background:
- Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.
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